Selected Publications

Below are highlighted publications by Dr. D’Armiento. For a complete list of Dr. D’Armiento’s publications, please click here.

D’Armiento J, Dalal SS, Okada Y, Berg RA, Chada K. Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema. Cell. 1992;71:955-61.

Imai K, Dalal SS, Chen ES, Downey R, Schulman LL, Ginsburg M, D’Armiento J. Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema. American Journal of Respiratory and Critical Care Medicine. 2001;163(3 Pt 1):786-91.

Lemaitre V, O’Byrne TK, Borczuk AC, Okada Y, Tall AR, D’Armiento J. ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis. The Journal of Clinical Investigation. 2001;107:1227-34.

Mercer BA, Kolesnikova N, Sonett J, D’Armiento J. Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke. The Journal of Biological Chemistry. 2004;279:17690-6.

D’Armiento J, Imai K, Schiltz J, Kolesnekova N, Sternberg D, Benson K, Pardo A, Selman M, Smolarek T, Vundavalli M, Sonnet J, Szabolcs M, Chada K. Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis. Cancer Research. 2007;67:1902-9.

Foronjy R, Imai K, Shiomi T, Mercer B, Sklepkiewicz P, Thankachen J, Bodine P, D’Armiento J. The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema. The American Journal of Pathology. 2010;177:598-607.

Elkington P, Shiomi T, Breen R, Nuttall RK, Ugarte-Gil CA, Walker NF, Saraiva L, Pedersen B, Mauri F, Lipman M, Edwards DR, Robertson BD, D’Armiento J, Friedland JS. MMP-1 drives immunopathology in human tuberculosis and transgenic mice. The Journal of Clinical Investigation. 2011;121:1827-33.

Geraghty P, Dabo AJ, D’Armiento J. TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease. The Journal of Biological Chemistry. 2011;286:30211-8.

Goldklang M, Golovatch P, Zelonina T, Trischler J, Rabinowitz D, Lemaître V, D’Armiento J. Activation of the TLR4 signaling pathway and abnormal cholesterol efflux lead to emphysema in ApoE-deficient mice. American Journal of Physiology Lung Cellular and Molecular Physiology. 2012;302(11):1200-8.

Wallace AM, Mercer BA, He J, Foronjy RF, Accili D, Sandford AJ, Paré PD, D’Armiento JM. Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study. Respiratory Research. 2012;13:79.

Morishita A, Zaidi MR, Mitoro A, Sankarasharma D, Szabolcs M, Okada Y, D’Armiento J, Chada K. HMGA2 is a driver of tumor metastasis. Cancer Research. 2013;73(14):4289-99.

Brehm A, Geraghty P, Garcia-Arcos I, D’Armiento J, Eden E, Foronjy R. Loss of plasma phospholipid transfer protein (PLTP) activity enhances inflammatory responses to cigarette smoke in the lung. European Respiratory Journal. 2013;42(Suppl 57):1813.

Cunningham I, Hamele-Bena D, Shiomi T, Emerson S, Silva JM, D’Armiento JM, Weeraratna AT. (2014). Liquid to solid: Leukemic breast tumors assume the morphologic and genetic characteristics of breast cancer. Cancer Research. 2013;74(Suppl 19): 3996.

Ishibashi M, Sayers S, D’Armiento JM, Tall AR, Welch CL. TLR3 deficiency protects against collagen degradation and medial destruction in murine atherosclerotic plaques. Atherosclerosis. 2013;229(1): 52-61.

Cunningham I, Shiomi T, D’Armiento JM, Rui H, Cordon-Cardo C, Hamele-Bena D. Hiding from chemo: Leukemic cells forming tumors to survive. Cancer Research. 2013;73(8 Supplement): 1096.

Woode D, Shiomi T, D’Armiento J. Collagenolytic Matrix Metalloproteinases in Chronic Obstructive Lung Disease and Cancer. Cancers. 2015;7(1): 329-341.

D’Armiento J, Shiomi T, Marks S, Geraghty P, Sankarasharma D, Chada K. Mesenchymal Tumorigenesis Driven by TSC2 Haploinsufficiency Requires HMGA2 and Is Independent of mTOR Pathway Activation. Cancer Research. 2016;76(4): 844-854.